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Etodolac

Cat. No. M5634
Etodolac Structure
Size Price Availability Quantity
50mg USD 60 In stock
100mg USD 90 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) and a COX inhibitor, used for the treatment of inflammation and pain.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 287.35
Formula C17H21NO3
CAS Number 41340-25-4
Purity >99%
Solubility 58 mg/mL in DMSO
Storage at -20°C
References

A window-of-opportunity biomarker study of etodolac in resectable breast cancer.
Schwab RB, et al. Cancer Med. 2015 Oct;4(10):1583-8. PMID: 26275572.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Etodolac supplier, COX, inhibitors

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