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Ethyl β-D-apiofuranoside

Cat. No. M17450
Ethyl β-D-apiofuranoside Structure
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Biological Activity

Ethyl β-D-apiofuranoside (Oil)

Chemical Information
CAS Number 1932405-61-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Passent Mahmoud Abdel Baki, et al. Iran J Pharm Res. quareticctivity of S olidago canadensis cultivated ingypt and etermination of theostioactiveraction

[2] Jiaojiao Jiang, et al. Molecules. A Strategy for Preparative Separation of 10 Lignans from Justicia procumbens L. by High-Speed Counter-Current Chromatography

[3] Eutrophe Le Doux Kamto, et al. J Chromatogr A. Alternating isocratic and step gradient elution high-speed counter-current chromatography for the isolation of minor phenolics from Ormocarpum kirkii bark

[4] Mee Jung Jung, et al. Food Chem. Free radical scavenging and total phenolic contents from methanolic extracts of Ulmus davidiana

[5] Lisieux de Santana Julio, et al. Phytochemistry. Flavones and phenylpropanoids from a sedative extract of Lantana trifolia L

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