α-Lactose is the major sugar present in milk. Lactose exists in the form of two anomers, α and β. Lactose is a very important sugar because of its abundance in the milk of humans and domestic animals.
| Molecular Weight | 342.30 |
| Formula | C12H22O11 |
| CAS Number | 14641-93-1 |
| Solubility (25°C) | DMSO 20 mg/mL Water 30 mg/mL |
| Storage | 4°C, dry, sealed |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related Saccharides Products |
|---|
| 6-Deoxy-3-O-methyl-β-allopyranosyl
(1→4)-β-cymaronic acid δ-lactone
6-Deoxy-3-O-methyl-β-allopyranosyl (1→4)-β-cymaronic acid δ-lactone |
| Primeverose
Primeverose |
| Ethyl rutinoside
Ethyl rutinoside |
| 1,5-Anhydroglucitol
1,5-Anhydroglucitol |
| 3,6'-Disinapoylsucrose
3,6'-Disinapoylsucrose |
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