All AbMole products are for research use only, cannot be used for human consumption.
Etanercept is a dimer fusion protein that binds tumor necrosis factor (TNF) as a TNF inhibitor. Etanercept competitively inhibits the binding of TNF-α and TNF-β to TNF receptors on the cell surface, rendering tumor necrosis factor biologically inactive.
Immun Inflamm Dis. 2022 Dec;10(12):e734.
Etanercept alleviates psoriasis by reducing the Th17/Treg ratio and promoting M2 polarization of macrophages
Etanercept purchased from AbMole
Molecules. 2019 Oct 9;24(20).
M860, a Monoclonal Antibody against Human Lactoferrin, Enhances Tumoricidal Activity of Low Dosage Lactoferrin via Granzyme B Induction.
Etanercept purchased from AbMole
| Cell Experiment | |
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| Cell lines | |
| Preparation method | |
| Concentrations | |
| Incubation time | |
| Animal Experiment | |
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| Animal models | CIA rats |
| Formulation | |
| Dosages | 5 mg/kg |
| Administration | s.c. |
| Molecular Weight | 51234.33 |
| Formula | C2224H3475N621O698S36 |
| CAS Number | 185243-69-0 |
| Storage | -80°C for long term |
| Related TNF Receptor Products |
|---|
| Ozekibart
Ozekibart is an anti-TNFRSF10B monoclonal antibody. |
| TAPI-0
TAPI-0 is a TACE (TNF-α converting enzyme; ADAM17) inhibitor with an IC50 of 100 nM. |
| Semapimod tetrahydrochloride
Semapimod tetrahydrochloride (CNI-1493), an inhibitor of proinflammatory cytokine production, can inhibit TNF-α, IL-1β, and IL-6. |
| BMS-566394
BMS-566394 is a potent, exceptionally selective inhibitor of TNF-α converting enzyme (TACE). |
| APVO603
APVO603 is a dual agonist bispecific antibody employing a novel mechanism of action to simultaneously target 4-1BB (CD137) and OX40 (CD134), both members of the TNF-receptor family. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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