Free shipping on all orders over $ 500

Estropipate

Cat. No. M5627
Estropipate Structure
Synonym:

Piperazine estrone sulfate; Estrone sulfate piperazine salt

Size Price Availability Quantity
10mg USD 60 In stock
50mg USD 110 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Estropipate is a form of estrogen, used to treat symptoms of menopause, also used to prevent osteoporosis.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 436.56
Formula C22H22N2O5S
CAS Number 7280-37-7
Purity >98%
Solubility 36 mg/mL in DMSO
Storage at -20°C
References

Effects of estropipate treatment on plasma lipids and lipoprotein lipid composition in postmenopausal women.
Bagdade JD, et al, J Clin Endocrinol Metab. 1991 Feb;72(2):283-6. PMID: 1991799.

Related Estrogen Receptor Products
Relugolix

Relugolix, also known as TAK-385, is a luteinizing hormone-releasing hormone (LH-RH) receptor antagonist with an IC50 of 0.12 nM.

Elagolix sodium

Elagolix Soidum is a potent, selective, orally active, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with Kd value of 54 pM.

GDC-0810

GDC-0810 (Brilanestrant, ARN-81) is an orally bioavailable selective estrogen receptor degrader (SERD) with IC50 of 0.7 nM.

Tamoxifen

Tamoxifen is a estrogen receptor partial agonist/antagonist.

GSK 4716

GSK 4716 is a selective agonist with estrogen-related receptors ERRβ and ERRγ.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Estropipate, Piperazine estrone sulfate; Estrone sulfate piperazine salt supplier, Estrogen Receptor, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.