Elq-300 is an antimalarial drug available for biological research and is also an effective oral cytochrome BC1 complex (CYT BC1) reduction (Qi) site inhibitor.
Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
Molecular Weight | 475.84 |
Formula | C24H17ClF3NO4 |
CAS Number | 1354745-52-0 |
Purity | >98.5% |
Solubility | DMSO 10 mg/mL |
Storage | at -20°C |
Related Anti-infection Products |
---|
N-Glycolylneuraminic acid
N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs). |
Glycol chitosan
Glycol chitosan is a kind of chitosan derivative with hydrophilic glycol-branched. Glycol-chitosan enhances membrane permeability and lead in glycine Max Harosoy 63W cells. |
Sulfaquinoxaline sodium
Sulfaquinoxaline sodium (N'1-quinoxalin-2-ylsulphanilamide sodium, SQ-Na) is the sodium salt of sulfaquinoxaline, which is often used as a drug to prevent coccidiosis in poultry, swine, and sheep by inhibiting the synthesis of nucleic acids and proteins in microorganisms. |
6-Aminopenicillanic acid
6-Aminopenicillanic acid (6-APA) is the central component of penicillin β-lactam antibiotics which are generated by Penicillium. It is used as precursor for antibiotic compounds ampicillin and amoxicillin. |
Cefadroxil hydrate
Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.