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Echinatin

Cat. No. M4011

All AbMole products are for research use only, cannot be used for human consumption.

Echinatin Structure
Size Price Availability Quantity
5mg USD 80  USD80 In stock
10mg USD 140  USD140 In stock
20mg USD 230  USD230 In stock
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Quality Control & Documentation
Biological Activity

Echinatin is isolated from the Chinese herbal medicine licorice, chalcone, which has liver protection and anti-inflammatory effects. In rats, Echinatin can be rapidly absorbed and eliminated and is widely distributed, with an absolute bioavailability of about 6.81%.

Chemical Information
Molecular Weight 270.28
Formula C16H14O4
CAS Number 34221-41-5
Form Solid
Solubility (25°C) 10 mM in DMSO
Storage 2-8°C, protect from light
References

[1] Haijun Ran, et al. Echinatin mitigates H2O2-induced oxidative damage and apoptosis in lens epithelial cells via the Nrf2/HO-1 pathway

[2] Jieting Niu, et al. Cardioprotective Effect of Echinatin Against Ischemia/Reperfusion Injury: Involvement of Hippo/Yes-Associated Protein Signaling

[3] Guang Xu, et al. Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90

[4] Pan Hong, et al. Echinatin suppresses esophageal cancer tumor growth and invasion through inducing AKT/mTOR-dependent autophagy and apoptosis

[5] Minshi Liang, et al. Antioxidant Mechanisms of Echinatin and Licochalcone A

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