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Desogestrel

Cat. No. M5564
Desogestrel Structure
Synonym:

Cerazette, Desogen, Desogestrelum, Org-2969

Size Price Availability Quantity
10mg USD 63  USD70 In stock
50mg USD 135  USD150 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Desogestrel is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 310.47
Formula C22H30O
CAS Number 54024-22-5
Purity >98%
Solubility 62 mg/mL in DMSO
Storage at -20°C
References

Desogestrel versus danazol as preoperative treatment for hysteroscopic surgery: a prospective, randomized evaluation.
Laganà AS, et al. Gynecol Endocrinol. 2014 Nov;30(11):794-7. PMID: 24919887.

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  Catalog
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Keywords: Desogestrel, Cerazette, Desogen, Desogestrelum, Org-2969 supplier, Estrogen Receptor, inhibitors

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