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Cat. No. M6129
Dalfopristin Structure


Size Price Availability Quantity
1mg USD 260 In stock
5mg USD 860 In stock
10mg USD 1500 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Quinupristin/Dalfopristin(Q/D) is a combination of streptogramins B (Quinupristin) and streptogramins A (Dalfopristin) at 30:70 ratio. Quinupristin/Dalfopristin, a semisynthetic injectable streptogramin, is a combination of 2 synergistic antibiotic components that are derived from pristinamycin: a type B streptogramin (Quinupristin) and a type A streptogramin (Dalfopristin), in a 30:70 weight-to-weight ratio.

Cell Experiment
Cell lines
Preparation method
Incubation time
Animal Experiment
Animal models Eighteen New Zealand white rabbits
Formulation 5% dextrose water
Dosages 100 mg/mL
Administration i.v.
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 690.85
Formula C34H50N4O9S
CAS Number 112362-50-2
Purity >98%
Solubility 30 mg/mL in DMSO
Storage at -20°C

Genetic features of livestock-associated Staphylococcus aureus ST9 isolates from Chinese pigs that carry the lsa(E) gene for quinupristin/dalfopristin resistance.
Yan X, et al, Int J Med Microbiol. 2016 Dec;306(8):722-729. PMID: 27528592.

Safety of intravitreal quinupristin/dalfopristin in an animal model.
Giordano VE, et al. Int J Ophthalmol. 2016 Mar 18;9(3):373-8. PMID: 27158605.

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Keywords: Dalfopristin, RP54476 supplier, inhibitors

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