D-Lactate dehydrogenase is an oxidoreductase widely found in bacteria and fungi that acts on donor CH-OH groups using NAD+ or NADP+ as an acceptor and also catalyzes the oxidation of D-lactate to pyruvate.
| CAS Number | 9028-36-8 |
| Form | Solid |
| Storage | 2-8°C |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related Dehydrogenase Products |
|---|
| MTHFD2-IN-4
MTHFD2-IN-4, tricyclic coumarin derivative, is a potent MTHFD2 inhibitor. |
| MTHFD2-IN-4 sodium
MTHFD2-IN-4 sodium, tricyclic coumarin derivative, is a potent MTHFD2 inhibitor. |
| MTHFD2-IN-3
MTHFD2-IN-3 is a potent methylenetetrahydrofolate dehydrogenase (MTHFD2) inhibitor. |
| MTHFD2-IN-2
MTHFD2-IN-2 is a potent methylenetetrahydrofolate dehydrogenase (MTHFD2) inhibitor. |
| MTHFD2-IN-1
MTHFD2-IN-1 is a potent methylenetetrahydrofolate dehydrogenase (MTHFD2) inhibitor. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
