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Coronatine

Cat. No. M31177
Coronatine Structure
Synonym:

COR

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Biological Activity

Coronatine is an N-acyl amino acid present in Pseudomonas syringae and also a novel plant growth regulator. In addition, Coronatine is also a structural analog of jasmonic acid (JA), which improves plant resistance to low temperature stress and other abiotic stresses.

Chemical Information
Molecular Weight 319.4
Formula C18H25NO4
CAS Number 62251-96-1
Form Solid
Storage -20°C, protect from light
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Rui He, et al. J Integr Plant Biol. Coronatine promotes maize water uptake by directly binding to the aquaporin ZmPIP2;5 and enhancing its activity

[2] Ziyan Liu, et al. Int J Mol Sci. Coronatine Enhances Chilling Tolerance of Tomato Plants by Inducing Chilling-Related Epigenetic Adaptations and Transcriptional Reprogramming

[3] Min Gao, et al. Sci Rep. Coronatine is more potent than jasmonates in regulating Arabidopsis circadian clock

[4] Xueqing Geng, et al. Planta. The phytotoxin coronatine is a multifunctional component of the virulence armament of Pseudomonas syringae

[5] Xiu-Fang Xin, et al. Annu Rev Phytopathol. Pseudomonas syringae pv. tomato DC3000: a model pathogen for probing disease susceptibility and hormone signaling in plants

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Keywords: Coronatine, COR supplier, Plant growth regulators, inhibitors, activators


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