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Potassium carbonate

Cat. No. M40895
Potassium carbonate Structure
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Biological Activity

Potassium carbonate is a common potassium salt as well as a common potassium fertilizer.

Chemical Information
Molecular Weight 138.21
Formula K2CO3
CAS Number 584-08-7
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Ksenia Aaron et al. Cochrane Database Syst Rev. Ear drops for the removal of ear wax

[2] Jan Gohla et al. Mar Pollut Bull. Potassium carbonate (K2CO3) - A cheap, non-toxic and high-density floating solution for microplastic isolation from beach sediments

[3] Michelle N LeMaster et al. Meat Sci. Potassium carbonate improves fresh pork quality characteristics

[4] Ishani Lakshika Hettiarachchi et al. Tetrahedron Lett. Potassium carbonate-mediated β-selective anomeric O-alkylation with primary electrophiles: Application to the synthesis of glycosphingolipids

[5] Suying Wang et al. Dalton Trans. Dry hydrated potassium carbonate for effective CO2 capture

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