Free shipping on all orders over $ 500

Coelonin

Cat. No. M17352
Coelonin Structure
Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Coelonin

Chemical Information
CAS Number 82344-82-9
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Chunchun Zhang, et al. Mediators Inflamm. Anti-Inflammatory Effect Fraction of Bletilla striata and Its Protective Effect on LPS-Induced Acute Lung Injury

[2] Wen Cheng, et al. Eur J Pharmacol. Inhibition of inflammation-induced injury and cell migration by coelonin and militarine in PM 2.5-exposed human lung alveolar epithelial A549 cells

[3] Fusheng Jiang, et al. Int J Mol Sci. Coelonin, an Anti-Inflammation Active Component of Bletilla striata and Its Potential Mechanism

[4] Fu-Sheng Jiang, et al. Zhongguo Zhong Yao Za Zhi. [Comparison of contents of three active ingredients in Bletilla striata from different sources]

[5] Ya-Ping Wu, et al. Nat Prod Res. Phenolic compounds from the stems of Flickingeria fimbriata

Related Phenols Products
Dihydrodehydrodiconiferyl alcohol

Dihydrodehydrodiconiferyl alcohol is a kind of neolignan. Dihydrodehydrodiconiferyl alcohol can be isolated from Anogeissus acuminata. Dihydrodehydrodiconiferyl alcohol has specific cytotoxic activity on melanoma cancer cell line.

Dihydrosinapyl alcohol

Dihydrosinapyl alcohol, a natural product, can be obtained from lignocellulose by hydrogenation and hydrogenolysis.

Neoisoliquiritin

Neoisoliquiritin is a bioactive component isolated from Glycyrrhiza uralensis.

Porson

Porson

Cotoin

Cotoin

  Catalog
Abmole Inhibitor Catalog




Keywords: Coelonin supplier, Phenols, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.