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Ciprofloxacin hydrochloride

Cat. No. M10429
Ciprofloxacin hydrochloride Structure
Synonym:

CPX; Cetraxal; Ciloxan; Cipro; Bay-09867 hydrochloride

Size Price Availability Quantity
100mg USD 54  USD60 In stock
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Quality Control
  • Current batch:
  • Purity >98.5%
  • COA
  • MSDS
Biological Activity

Ciprofloxacin hydrochloride is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases).

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 367.8
Formula C17H18FN3O3.HCl
CAS Number 93107-08-5
Purity >98.5%
Solubility Water 60 mg/mL
Storage 2-8°C, dry, sealed
References

Ciprofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use
D M Campoli-Richards, et al. Dгυgs. 1988 Apr;35(4):373-447. PMID: 3292209.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Ciprofloxacin hydrochloride, CPX; Cetraxal; Ciloxan; Cipro; Bay-09867 hydrochloride supplier, Antibiotic, inhibitors

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