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Chlorimuron ethyl

Cat. No. M21981
Chlorimuron ethyl Structure
Size Price Availability Quantity
1g USD 95  USD95 In stock
5g USD 225  USD225 In stock
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Quality Control & Documentation
Biological Activity

Chlorimuron ethyl

Chemical Information
Molecular Weight 414.82
Formula C15H15ClN4O6S
CAS Number 90982-32-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Zhixiong Yu, et al. Int J Mol Sci. A Novel Pathway of Chlorimuron-Ethyl Biodegradation by Chenggangzhangella methanolivorans Strain CHL1 and Its Molecular Mechanisms

[2] Zhixiong Yu, et al. Microbiol Spectr. Whole-Genome Sequencing of a Chlorimuron-Ethyl-Degrading Strain: Chenggangzhangella methanolivorans CHL1 and Its Degrading Enzymes

[3] Hailian Zang, et al. Microorganisms. Bioremediation of Historically Chlorimuron-Ethyl-Contaminated Soil by Co-Culture Chlorimuron-Ethyl-Degrading Bacteria Combined with the Spent Mushroom Substrate

[4] Cheng Zhang, et al. Ecotoxicol Environ Saf. Transcriptomic analysis of Chlorimuron-ethyl degrading bacterial strain Klebsiella jilinsis 2N3

[5] Xiong Pan, et al. Ecotoxicol Environ Saf. Biodegradation and detoxification of chlorimuron-ethyl by Enterobacter ludwigii sp. CE-1

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