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ChlordehydroMethyl Testosterone

Cat. No. M6122
ChlordehydroMethyl Testosterone Structure
Size Price Availability Quantity
10mg USD 110 In stock
50mg USD 400 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Circulating testosterone levels decline progressively with age, starting in the second and third decade of life, owing to defects at all levels of the hypothalamic-pituitary-testicular axis. In cohort studies, testosterone levels are associated weakly but consistently with muscle mass, strength, physical function, anaemia, BMD and bone quality, visceral adiposity, and with the risk of diabetes mellitus, coronary artery disease, falls, fractures and mortality.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 334.88
Formula C20H27ClO2
CAS Number 2446-23-3
Purity >99%
Solubility 10 mM in DMSO
Storage at -20°C
References

Risks and benefits of testosterone therapy in older men.
Spitzer M, et al. Nat Rev Endocrinol. 2013 Jul;9(7):414-24. PMID: 23591366.

Testosterone and sport: current perspectives.
Wood RI, et al. Horm Behav. 2012 Jan;61(1):147-55. PMID: 21983229.

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