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Cefquinome sulfate

Cat. No. M9030
Cefquinome sulfate Structure
Size Price Availability Quantity
50mg USD 150 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Cefquinome sulfate is a broad-spectrum fourth-generation cephalosporin antibiotic. Cefquinome sulphate's antimicrobial potency and extensive antibacterial spectrum result from the introduction of a methoxyimino-aminothiazolyl moiety into the acyl side chain.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 626.68
Formula C23H25N6O5S2.HSO4
CAS Number 118443-89-3
Purity >98%
Solubility DMSO: ≥ 60 mg/mL
Storage at -20°C
References

Stability Study and Kinetic Monitoring of Cefquinome Sulfate Using Cyclodextrin-Based Ion-Selective Electrode: Application to Biological Samples.
Yehia AM, et al. J AOAC Int. 2016 Jan-Feb;99(1):73-81. PMID: 26822094.

Ratio manipulating spectrophotometry versus chemometry as stability indicating methods for cefquinome sulfate determination.
Yehia AM, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2016 Jan 15;153:231-40. PMID: 26318697.

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  Catalog
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