Free shipping on all orders over $ 500

Cefamandole sodium

Cat. No. M22426
Cefamandole sodium Structure
Size Price Availability Quantity
10mg USD 100  USD100 In stock
25mg USD 245  USD245 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Cefamandole sodium

Chemical Information
Molecular Weight 484.48
Formula C18H17N6NaO5S2
CAS Number 30034-03-8
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Shuangqi Cai, et al. An Acad Bras Cienc. Differential Proteomic and Genomic Comparison of Resistance Mechanism of Pseudomonas aeruginosa to Cefoperazone Sodium/Sulbactam Sodium

[2] V Das Gupta, et al. Am J Hosp Pharm. Stability of cefamandole nafate and cefoxitin sodium solutions

[3] J A Bosso, et al. Am J Hosp Pharm. Stability of clindamycin phosphate and ceftizoxime sodium, cefoxitin sodium, cefamandole nafate, or cefazolin sodium in two intravenous solutions

[4] J C Hall, et al. Arch Surg. A comparison of the roles of cefamandole and ceftriaxone in abdominal surgery

[5] J M Indelicato, et al. J Pharm Sci. Conversion of cefamandole nafate to cefamandole sodium

Related Antibiotic Products
TH-Z145

TH-Z145 is a lipophilic GGPPS inhibitor (GGPPS IC50 = 210 nM). TH-Z145 is a very lipophilic bisphosphonate that lacks the cationic center essential for FPPS inhibition and is thus a specific GGPPS inhibitor (FPPS IC50 >30 mM). TH-Z145 exhibited strong prophylactic effects in a pathogenic influenza model.

TH-Z93

TH-Z93, a lipophilic bisphosphonate, is an FPPS inhibitor (IC50 = 90 nM). TH-Z93 exhibits potent efficacy, increasing both antibody titers and avidity. TH-Z93 exhibited strong prophylactic effects in a pathogenic influenza model.

Ningnanmycin

Ningnanmycin is a cytosine nucleoside peptide antibiotic, which is a highly effective, low-toxic, non-accumulative, broad-spectrum fungicide.

Sulfacytine

Sulfacytine is a short-acting sulfonamide antibiotic.

Cefcapene pivoxil hydrochloride

Cefcapene pivoxil hydrochloride, the pivalate ester precursor form of Cefcapene, is an orally active third-generation cephalosporin with a wide spectrum of anti-bacterial activity. Cefcapene pivoxil hydrochloride has the potential for the palmoplantar pustulosis (PPP) research.

  Catalog
Abmole Inhibitor Catalog




Keywords: Cefamandole sodium supplier, Antibiotic, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.