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Cebranopadol

Cat. No. M5065
Cebranopadol Structure
Synonym:

GRT-6005

Size Price Availability Quantity
2mg USD 180 In stock
5mg USD 270 In stock
10mg USD 350 In stock
50mg USD 930 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Cebranopadol has successfully completed initial proof-of-concept studies in nociceptive and neuropathic pain with further Phase II studies planned prior to initiation of Phase III studies.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 378.48
Formula C24H27FN2O
CAS Number 863513-91-1
Purity >99%
Solubility 10 mM in DMSO
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Cebranopadol, GRT-6005 supplier, Opioid Receptor, inhibitors

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