Free shipping on all orders over $ 500

Carteolol hydrochloride

Cat. No. M3656
Carteolol hydrochloride Structure
Synonym:

Carteolol HCl

Size Price Availability Quantity
50mg USD 150 In stock
100mg USD 250 In stock
Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Carteolol hydrochloride is a non-selective beta blocker. Carteolol hydrochloride at 1 mmol/L (P<0.05) significantly inhibites H2O2-induced cell damage and is able to scavenge O2 (EC50 value: 48 mmol/L). Carteolol hydrochloride has a protective action against UVB-induced HCEC damage, and its radical scavenging ability may be an important basis for this effect.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 328.83
Formula C16H25ClN2O3
CAS Number 51781-21-6
Purity >99%
Solubility DMSO
Storage at -20°C
References

Carteolol hydrochloride protects human corneal epithelial cells from UVB-induced damage in vitro.
Kuwahara K, et al. Cornea. 2005 Mar;24(2):213-20. PMID: 15725891.

Related Adrenergic Receptor Products
Xylometazoline HCl

Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM.

Xylazine HCl

Xylazine is an α2-Adrenergic receptor agonist, used as a sedative and muscle relaxant.

Tizanidine HCl

Tizanidine hydrochloride is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.

Terazosin HCl

Terazosin is a selective alpha-1 antagonist used for treatment of symptoms of an enlarged prostate (BPH). It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls.

Terazosin HCl Dihydrate

Terazosin HCl is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH).

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Carteolol hydrochloride, Carteolol HCl supplier, Adrenergic Receptor, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.