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Calf thymus DNA

Cat. No. M9295
Calf thymus DNA Structure
Synonym:

Thymonucleic acid

Size Price Availability
5mg USD 110  USD110 Out of stock
10mg USD 180  USD180 Out of stock
25mg USD 400  USD400 Out of stock
50mg USD 720  USD720 Out of stock
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Quality Control & Documentation
Biological Activity

Calf thymus DNA is high quality double-stranded template DNA isolated from the thymus of male and female calves.

Chemical Information
CAS Number 91080-16-9
Solubility (25°C) Water 15 mg/mL
Storage 4°C, protect from light
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Liu F, et al. Sci Rep. Cytotoxicity of Aconitum alkaloid and its interaction with calf thymus DNA by multi-spectroscopic techniques.

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Keywords: Calf thymus DNA, Thymonucleic acid supplier, inhibitors, activators


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