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BMS 493 is an inverse pan-RAR agonist. Retinoic acid receptors (RARs) are ligand-dependent transcription factors that control a number of physiological processes. RARs exert their functions by regulating gene networks controlling cell growth, differentiation, survival, and death.
| Molecular Weight | 404.5 |
| Formula | C29H24O2 |
| CAS Number | 215030-90-3 |
| Solubility (25°C) | DMSO: ≥20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Vera Clemens, et al. Anti-inflammatory effects of minocycline are mediated by retinoid signaling
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