Betamethasone is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.
| Molecular Weight | 392.46 |
| Formula | C22H29FO5 |
| CAS Number | 378-44-9 |
| Form | Solid |
| Solubility (25°C) | DMSO 49 mg/mL |
| Storage | 2-8°C, protect from light |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related GCR Products |
|---|
| ORIC-101
ORIC-101 is a potent and selective glucocorticoid receptor antagonist with an EC50 value of 5.6 nM and anticancer activity. |
| Mometasone Furoate Monohydrate
Mometasone Furoate Monohydrate is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic activity. |
| RU 26988
RU 26988 is a highly specific glucocorticoid receptor agonist. |
| HP210
HP210 is a selective glucocorticoid receptor modulator (SGRM). |
| Glucocorticoid receptor modulator 2
Glucocorticoid receptor modulator 2 is a glucocorticoid receptor modulator, with an IC50 value less than 100 nM. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
