β-Cyclodextrin affects the formation of isomerization products during peptide deamidation.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Source||J Exp Med (2017). Figure 3. Cyclodextrin (Abmole Bioscience)|
|Cell Lines||CD45-positive cells|
|Incubation Time||2 wk|
|Results||Atorvastatin was dissolved at a final concentration of 20 mg/ml in cyclodextrin (5 mg/m). The contribution of cholesterol and BA metabolism to the phenotype was next assessed using an inhibitor of the HMGCoA reductase (HMG CR) atorvastatin (in short, statin).|
J Exp Med. 2017 May 1;214(5):1387-1409.
Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation
β-Cyclodextrin purchased from AbMole
Letter: β-Cyclodextrin affects the formation of isomerization products during peptide deamidation.
Volmer DA,et.al. Eur J Mass Spectrom (Chichester, Eng). 2015;701-5. PMID: 26353992.
Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in treating idiopathic pulmonary fibrosis.
Wilfortrine is an immunomodulatory compound isolated from Tripterygium wilfordii.
Etanercept is a dimeric fusion protein consisting of two ligand-binding domains of human p75 tumor necrosis factor receptor and the human IgG1 Fc portion.
Tocilizumab is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD.
Lambrolizumabis a potent, highly selective, fully humanized immunoglobulin (Ig) G4-kappa monoclonal antibody against PD-1 with potential immune checkpoint inhibitory and antineoplastic activities. MW : 146.286 KD.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.