β-Cyclodextrin affects the formation of isomerization products during peptide deamidation.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Source||J Exp Med (2017). Figure 3. Cyclodextrin (Abmole Bioscience)|
|Cell Lines||CD45-positive cells|
|Incubation Time||2 wk|
|Results||Atorvastatin was dissolved at a final concentration of 20 mg/ml in cyclodextrin (5 mg/m). The contribution of cholesterol and BA metabolism to the phenotype was next assessed using an inhibitor of the HMGCoA reductase (HMG CR) atorvastatin (in short, statin).|
J Exp Med 2017 May 1;214(5):1387-1409.
Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation
β-Cyclodextrin purchased from AbMole
Letter: β-Cyclodextrin affects the formation of isomerization products during peptide deamidation.
Volmer DA,et.al. Eur J Mass Spectrom (Chichester, Eng). 2015;701-5. PMID: 26353992.
MTX-211 is a enamide hydrate.
GSK369796 shows antimalerial activity with IC50 values of 11.2 nM for 3D7 strain, 12.6 nM for HB3 strain, 17.6 nM for K1 strain.
An analog of aromatic cytokinins, the 2,6,9-trisubstituted purine derivative bohemine, was applied to cultures of mouse hybridoma cells in order to analyze its capacity of suppressing cell growth and maintaining or enhancing the production of monoclonal antibody.
This compound belongs to the class of organic compounds known as n-alkylindoles. These are compounds containing an indole moiety that carries an alkyl chain at the 1-position.
ARQ 087 is a novel, ATP competitive, small molecule, multi-kinase inhibitor with potent in vitro and in vivo activity against FGFR addicted cell lines and tumors. ARQ 087 exhibited IC50 values of 1.8 nM for FGFR2, and 4.5 nM for FGFR1 and 3.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.