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Berbamine

Cat. No. M4756

All AbMole products are for research use only, cannot be used for human consumption.

Berbamine Structure
Size Price Availability Quantity
1mg USD 25  USD25 In stock
5mg USD 47  USD47 In stock
10mg USD 75  USD75 In stock
20mg USD 120  USD120 In stock
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Quality Control & Documentation
Biological Activity

Berbamine is a natural compound extracted from the traditional Chinese medicine Phellodendron amurense, which has anti-tumor, immunomodulatory and cardiovascular effects. Berbamine is a calcium channel blocker.

Chemical Information
Molecular Weight 608.72
Formula C37H40N2O6
CAS Number 478-61-5
Form Solid
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bin-Bin Yu, et al. Effect of berbamine on invasion and metastasis of human liver cancer SMMC-7721 cells and its possible mechanism

[2] Yu Jin Kim, et al. Antiangiogenic and antitumor potential of berbamine, a natural CaMKIIγ inhibitor, against glioblastoma

[3] Lihong Huang, et al. Berbamine inhibits SARS-CoV-2 infection by compromising TRPMLs-mediated endolysosomal trafficking of ACE2

[4] Chenglin Han, et al. Berbamine Suppresses the Progression of Bladder Cancer by Modulating the ROS/NF- κ B Axis

[5] Alexandria M Hudson, et al. Berbamine Analogs Exhibit Differential Protective Effects From Aminoglycoside-Induced Hair Cell Death

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Keywords: Berbamine supplier, NF-κB, inhibitors, activators

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