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Benzophenonetetracarboxylic acid

Cat. No. M21900
Benzophenonetetracarboxylic acid Structure
Size Price Availability Quantity
10mg USD 60  USD60 In stock
50mg USD 120  USD120 In stock
100mg USD 180  USD180 In stock
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Quality Control & Documentation
Biological Activity

Benzophenonetetracarboxylic acid

Chemical Information
Molecular Weight 358.26
Formula C17H10O9
CAS Number 2479-49-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Yabo Fu, et al. Colloids Surf B Biointerfaces. Preparation and performance of a BTDA-modified polyurea microcapsule for encapsulating avermectin

[2] Xiaohui Yu, et al. Polymers (Basel). Mixed Rigid and Flexible Component Design for High-Performance Polyimide Films

[3] Krzysztof Kochel, et al. Bioorg Med Chem Lett. Evaluation of biological properties of 3,3',4,4'-benzophenonetetracarboxylic dianhydride derivatives and their ability to inhibit hexokinase activity

[4] Ruojin Liu, et al. J Nanosci Nanotechnol. Preparation of Polyimide/MWCNT Nanocomposites via Solid State Shearing Pulverization (S3P) Processing

[5] Natalya N Saprygina, et al. J Phys Chem A. Effect of amino group charge on the photooxidation kinetics of aromatic amino acids

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