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Armepavine

Cat. No. M4230

All AbMole products are for research use only, cannot be used for human consumption.

Armepavine Structure
Size Price Availability Quantity
10mg USD 400  USD400 In stock
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Quality Control & Documentation
Biological Activity

Armepavine is an active compound from Nelumbo Nucifera, which not only has anti-inflammatory effect on human peripheral blood monocytes, but also has immunosuppressive effect on T lymphocytes and lupus nephritis mice. Armepavine inhibits TNF-α - induced MAPK and NF-κB signaling cascade.

Chemical Information
Molecular Weight 313.39
Formula C19H23NO3
CAS Number 524-20-9
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 4°C, protect from light, dry, sealed
References

[1] Peiwu Geng, et al. Determination of armepavine in mouse blood by UPLC-MS/MS and its application to pharmacokinetic study

[2] Shuk-Man Ka, et al. (S)-armepavine from Chinese medicine improves experimental autoimmune crescentic glomerulonephritis

[3] Chih-Peng Liu, et al. (S)-armepavine inhibits human peripheral blood mononuclear cell activation by regulating Itk and PLCgamma activation in a PI-3K-dependent manner

[4] Chih-Peng Liu, et al. Inhibition of (S)-armepavine from Nelumbo nucifera on autoimmune disease of MRL/MpJ-lpr/lpr mice

[5] Guey-Mei Jow, et al. Armepavine oxalate induces cell death on CCRF-CEM leukemia cell line through an apoptotic pathway

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Keywords: Armepavine supplier, NF-κB, inhibitors, activators

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