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Aristolochic acid A (Aristolochic acid I; TR 1736) is the principal component of the plant extract Aristolochic Acids, found in Aristolochia and Asarum herbs. Aristolochic acid A significantly decreased activator protein 1 (AP-1) and NF-κB activity. Aristolochic acid A reduces the expression of bladder cancer-associated BLCAP gene in human cells.
| Molecular Weight | 341.27 |
| Formula | C17H11NO7 |
| CAS Number | 313-67-7 |
| Solubility (25°C) | DMSO 16 mg/mL |
| Storage | 2-8°C, protect from light |
[3] Arthur P Grollman. Aristolochic acid nephropathy: Harbinger of a global iatrogenic disease
[4] Frdric D Debelle, et al. Aristolochic acid nephropathy: a worldwide problem
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