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ABM-3627

Cat. No. M9132
ABM-3627 Structure
Synonym:

Mutant EGFR inhibitor

Size Price Availability Quantity
10mM*1mL In DMSO USD 465 In stock
2mg USD 285 In stock
5mg USD 405 In stock
10mg USD 580 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

ABM-3627, also known as Mutant EGFR inhibitor, is a selective and potent Mutated EGFR inhibitor. ABM-3627(Mutant EGFR inhibitor) inhibits EGFRL858R, EGFRExon 19 deletion and EGFRT790M.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 520.03
Formula C27H30ClN7O2
CAS Number 1421373-62-7
Purity >98%
Solubility DMSO 10 mM
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: ABM-3627, Mutant EGFR inhibitor supplier, EGFR/HER2, inhibitors

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