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A 412997 dihydrochloride

Cat. No. M6366

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A 412997 dihydrochloride Structure
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5mg USD 230  USD230 Custom Synthesis
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Biological Activity

A 412997 dihydrochloride is a selective agonist for the dopamine D4 receptor (Ki values are 7.9 and 12.1 nM for human D4 and rat D4 receptors). Displays no affinity (<1000 nM) for other dopamine receptors. Shows efficacy in rat models of ADHD and short-term memory.

Chemical Information
Molecular Weight 382.33
Formula C19H23N3O.2HCl
CAS Number 1347744-96-0
Solubility (25°C) Water 38.23 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Vernica Casad-Anguera, et al. Heteromerization between α 2A adrenoceptors and different polymorphic variants of the dopamine D 4 receptor determines pharmacological and functional differences. Implications for impulsive-control disorders

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Keywords: A 412997 dihydrochloride supplier, Dopamine Receptor, inhibitors, activators

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