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Sulfacetamide

Cat. No. M19873
Sulfacetamide Structure
Size Price Availability Quantity
500mg USD 48  USD48 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Sulfacetamide Sodium is an anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 214.24
Formula C8H10N2O3S
CAS Number 144-80-9
Purity >99%
Solubility DMSO 43 mg/mL
Storage at -20°C
References

[1] Yaoguang Guo, et al. RSC Adv. Insights into antimicrobial agent sulfacetamide transformation during chlorination disinfection process in aquaculture water

[2] Ola R Shehab, et al. Spectrochim Acta A Mol Biomol Spectrosc. Spectroscopic investigation of π-acceptors in the determination and photoinduced degradation of Sulfacetamide

[3] Luis J Borda, et al. J Dermatolog Treat. Treatment of seborrheic dermatitis: a comprehensive review

[4] Manal Abokwidir, et al. Skin Appendage Disord. Rosacea Management

[5] William Abramovits, et al. Skinmed. Sulfur/sodium sulfacetamide preparations

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