Free shipping on all orders over $ 500

8-Prenylkaempferol

Cat. No. M16676
8-Prenylkaempferol Structure
Size Price Availability Quantity
5mg USD 680  USD680 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

8-Prenylkaempferol

Chemical Information
CAS Number 28610-31-3
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Jang Hoon Kim, et al. J Enzyme Inhib Med Chem. Kushenol A and 8-prenylkaempferol, tyrosinase inhibitors, derived from Sophora flavescens

[2] Li-Man Ma, et al. Biomed Chromatogr. The profiling and identification of the metabolites of 8-prenylkaempferol and a study on their distribution in rats by high-performance liquid chromatography with diode array detection combined with electrospray ionization ion trap time-of-flight multista䲧盷Ỵ相㧀盶羹甗

[3] Wen-Fei Chiou, et al. Life Sci. 8-Prenylkaempferol accelerates osteoblast maturation through bone morphogenetic protein-2/p38 pathway to activate Runx2 transcription

[4] Wen-Fei Chiou, et al. Evid Based Complement Alternat Med. 8-Prenylkaempferol Suppresses Influenza A Virus-Induced RANTES Production in A549 Cells via Blocking PI3K-Mediated Transcriptional Activation of NF-κB and IRF3

[5] Chien-Chih Chen, et al. Eur J Pharmacol. 8-Prenylkaempferol suppresses inducible nitric oxide synthase expression through interfering with JNK-mediated AP-1 pathway in murine macrophages

Related Flavonoids Products
6''-O-Xylosyl-glycitin

6''-O-Xylosyl-glycitin is a natural isoflavonoid compound found in the flower of Pueraria thunbergiana Benth.

GB-1b

GB-1b

Santin

Santin

Ayanin

Ayanin

Fustin

Fustin

  Catalog
Abmole Inhibitor Catalog




Keywords: 8-Prenylkaempferol supplier, Flavonoids, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.