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18A

Cat. No. M6320

All AbMole products are for research use only, cannot be used for human consumption.

18A Structure

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Quality Control & Documentation
Biological Activity

18A is a hIV cell entry blocker. Binds gp120 and inhibits cell entry for a broad spectrum of HIV isolates. Exhibits no effect on the binding of CD4 or CCR5.

Chemical Information
Molecular Weight 313.33
Formula C14H11N5O2S
CAS Number 331261-50-8
Solubility (25°C) DMSO 31.33 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mingxin Cui, et al. MiR-18a-5p Facilitates Progression of Hepatocellular Carcinoma by Targeting CPEB3

[2] Hui-Min Liu, et al. Leonurine-Repressed miR-18a-5p/SOCS5/JAK2/STAT3 Axis Activity Disrupts CML malignancy

[3] Yongqiang Zhou, et al. miR-18a increases insulin sensitivity by inhibiting PTEN

[4] Nagore I Marn-Ramos, et al. miR-18a Inhibits BMP4 and HIF-1α Normalizing Brain Arteriovenous Malformations

[5] Kexin Shen, et al. The dual functional role of MicroRNA-18a (miR-18a) in cancer development

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Keywords: 18A supplier, inhibitors, activators

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