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1,7-Diepi-8,15-cedranediol

Cat. No. M17490
1,7-Diepi-8,15-cedranediol Structure
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Quality Control & Documentation
Biological Activity

1,7-Diepi-8,15-cedranediol

Chemical Information
CAS Number 40768-81-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] No authors listed. Nifurtimox

[2] No authors listed. (1-14C)-Triolein

[3] Zoran Milanović, et al. Sports Med. Effectiveness of High-Intensity Interval Training (HIT) and Continuous Endurance Training for VO2max Improvements: A Systematic Review and Meta-Analysis of Controlled Trials

[4] Elena Prokofyeva, et al. Acta Ophthalmol. Cataract prevalence and prevention in Europe: a literature review

[5] Shilpi Pandey, et al. Hum Reprod Update. Obstetric and perinatal outcomes in singleton pregnancies resulting from IVF/ICSI: a systematic review and meta-analysis

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