Catalog

TLR Toll-like Receptor

Inhibitors

Cat.No.	Name	Information
M9651	TLR4-IN-C34	C34 is a TLR4 inhibitor, which inhibited TLR4 in enterocytes and macrophages in vitro, and reduced systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis.
M9427	CU-CPT17e	CU-CPT17e is a potent multi-Toll-like receptor (TLR) agonist, which activates TLR3, TLR8 and TLR9.
M9289	E6446 dihydrochloride	E6446 dihydrochloride is a synthetic antagonist of TLR7 and TLR9.
M9204	Pam3CSK4	Pam3CSK4 is a Toll-like receptor 1/2 (TLR1/2) agonist.
M9063	TLR2-IN-C29	TLR2-IN-C29 is an inhibitor of TLR2/1 and TLR2/6 signaling.
M7189	Resiquimod	Resiquimod is a toll-like receptor 7 (TLR7) agonist.
M5800	Motolimod (VTX-2337)	Motolimod (VTX-2337) is a selective and potent Toll-like receptor (TLR) 8 agonist with EC50 of 100 nM, > 50-fold selectivity over TLR7. Phase 2.
M4838	TAK-242	TAK-242 (Resatorvid) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling.
M2728	GS-9620	GS-9620 is a potent and selective orally active small molecule agonist of Toll-like receptor 7.