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Src-bcr-Abl Src-bcr-Abl

Cat.No.  Name Information
M2331 PP2 (AGL 1879) PP2 is a selective inhibitor of Src-family tyrosine kinases with >10,000-fold selectivity over ZAP-70 and JAK2.
M1701 Dasatinib Dasatinib (BMS-354825) is a small molecule inhibitor of both the SRC and BCR/ABL tyrosine kinases, with IC50's for the isolated kinases of 0.55 and 3.0 nM, respectively.
M1648 AP24534 Ponatinib (AP24534) is a novel potent, orally available small molecule multitargeted kinase inhibitor of BCR-ABL, PDGFRα, c-Src, c-Kit, FGFR and VEGFR.
M1799 Imatinib Mesylate Imatinib Mesylate is a Bcr-Abl tyrosine kinase inhibitor, with IC50 values of 2.9 and 3.9 μM for the inhibition of T-cell proliferation stimulated by PHA and DCs respectively.
M1685 Bosutinib Bosutinib (SKI-606) is a novel Bcr-Abl inhibitor with IC50 values of 0.1 to 0.3 umol/L.
M3194 Nocodazole Nocodazole is a rapidly-reversible inhibitor of microtubule polymerization, also inhibits Abl, Abl(E255K) and Abl(T315I) with IC50 of 0.21 μM, 0.53 μM and 0.64 μM, respectively.
M20137 WAY-329689 WAY-329689 has ABL kinase inhibiting activities.
M20136 WAY-329686 WAY-329686 has ABL kinase inhibiting activities.
M20135 WAY-329685 WAY-329685 has ABL kinase inhibiting activities.
M20128 WAY-329424 WAY-329424 has ABL kinase inhibiting activities.
M20127 WAY-329423 WAY-329423 has ABL kinase inhibiting activities.
M20126 WAY-329412 WAY-329412 has ABL kinase inhibiting activities.
M20125 WAY-329410 WAY-329410 has ABL kinase inhibiting activities.
M20124 WAY-329356 WAY-329356 has ABL kinase inhibiting activities.
M20123 WAY-329341 WAY-329341 has ABL kinase inhibiting activities.
M20122 WAY-329340 WAY-329340 has ABL kinase inhibiting activities.
M20121 WAY-328158 WAY-328158 is a Inhibitor for BCR-ABL Kinase.
M20022 GI-560708 GI-560708 is a inhibitor of BCR-ABL tyrosine kinase.
M14914 Src Inhibitor 3 Src Inhibitor 3 is a potent, orally active c-terminal Src kinase (CSK) with IC50 values below 3 nM and 4 nM in CSK HTRF and Caliper assay, respectively.
M14909 1-Naphthyl PP1 hydrochloride 1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases. 1-Naphthyl PP1 hydrochloride inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively.
M8118 PD166326 PD166326 is an ATP-competitive inhibitor of BCR-ABL and Src kinases, inhibiting Src and Abl with IC50 values of 6 nM and 8 nM, respectively.




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