| Cat.No. | Name | Information |
|---|---|---|
| M2331 | PP2 (AGL 1879) | PP2 is a selective inhibitor of Src-family tyrosine kinases with >10,000-fold selectivity over ZAP-70 and JAK2. |
| M1701 | Dasatinib | Dasatinib (BMS-354825) is a small molecule inhibitor of both the SRC and BCR/ABL tyrosine kinases, with IC50's for the isolated kinases of 0.55 and 3.0 nM, respectively. |
| M1648 | AP24534 | Ponatinib (AP24534) is a novel potent, orally available small molecule multitargeted kinase inhibitor of BCR-ABL, PDGFRα, c-Src, c-Kit, FGFR and VEGFR. |
| M1799 | Imatinib Mesylate | Imatinib Mesylate is a Bcr-Abl tyrosine kinase inhibitor, with IC50 values of 2.9 and 3.9 μM for the inhibition of T-cell proliferation stimulated by PHA and DCs respectively. |
| M1685 | Bosutinib | Bosutinib (SKI-606) is a novel Bcr-Abl inhibitor with IC50 values of 0.1 to 0.3 umol/L. |
| M3194 | Nocodazole | Nocodazole is a rapidly-reversible inhibitor of microtubule polymerization, also inhibits Abl, Abl(E255K) and Abl(T315I) with IC50 of 0.21 μM, 0.53 μM and 0.64 μM, respectively. |
| M2603 | GNF-5 | GNF-5, an analogue of GNF-2 with improved pharmacokinetic properties, is a selective non-ATP competitive inhibitor of Bcr-Abl with an IC50 value of 0.22±0.1 uM (Wild type Abl). |
| M2571 | GNF-2 | GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl, shows no activity to Flt3-ITD, Tel-PDGFR, TPR-MET and Tel-JAK1 transformed tumor cells. |
| M2313 | Tirbanibulin (KX2-391) | Tirbanibulin (KX2-391) is a First-in-Class, highly selective non ATP-competitive Src inhibitor with GI50 of 9-60 nM in cancer cell lines . |
| M1991 | Bafetinib | Bafetinib (NS-187, INNO-406) is a novel second-generation dual Bcr-Abl/Lyn tyrosine kinase inhibitor. |
| M1912 | Nilotinib | Nilotinib (AMN107) is a small molecule Bcr-Abl kinase inhibitor with IC50 less than 30 nM. |
| M1702 | DCC-2036 | DCC-2036 is an ABL inhibitor with IC50 of 0.8 and 2 nM for u-ABL1native and p-ABL1native, respectively. |
| M1659 | Saracatinib | Saracatinib (AZD0530) is an orally active small molecule Src inhibitor. |
| M54849 | Asciminib hydrochloride | Asciminib (ABL001) hydrochloride is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM. |
| M54040 | Osteogenic Growth Peptide (10-14) | Osteogenic Growth Peptide (10-14) (OGP(10-14)), the C-terminal truncated pentapeptide of osteogenic growth peptide (OGP), retains the full OGP-like activity. |
| M50427 | Abl Cytosolic Substrate | Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ). |
| M50411 | Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH | Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). |
| M50410 | p60c-src substrate II | p60c-src substrate II is an efficient pentapeptide substrate for the tyrosine kinase pp60c-src. |
| M50409 | Caffeic acid-pYEEIE | Caffeic acid-pYEEIE, a non-phosphopeptide inhibitor, exhibits potent binding affinity for the GST-Lck-SH2 domain. |
| M50408 | Secretin, canine | Secretin, canine is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. |
| M50407 | RR-SRC | RR-SRC is a substrate for src-tyrosine-specific protein kinase. |
| M50406 | Tyrosine Kinase Peptide 1 | Tyrosine Kinase Peptide 1 is a control substrate peptide for c-Src assay. |
| M50176 | Saracatinib difumarate | Saracatinib (AZD0530) difumarate is a potent Src inhibitor with IC50 values of 2.7-11 nM for c-Src, Lck, c-YES, Lyn, Fyn, Fgr and Blk, and it is selective for other tyrosine kinases. |
| M44701 | 2-Hydroxy-3-methylanthraquinone | 2-Hydroxy-3-methylanthraquinone is a natural compound isolated from a water extract of Hedyotis diffusa WILLD. |
| M43530 | BT424 | BT424 is a specific HCK inhibitor. |
| M43529 | Lck Inhibitor III | Lck Inhibitor III is a potent Lck inhibitor, with an IC50 of 867 nM. |
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