|M5986||Suramin sodium salt||Suramin sodium salt is a polysulfonated naphthylurea that inhibits the binding of calmodulin to recognition sites on the ryanodine receptor-1 (IC50 = 4.9 μM), blocks G protein coupling to GPCRs, and non-selectively antagonizes P2 purinergic receptors (10-100 μM).|
|M3280||Clopidogrel||Clopidogrel (Plavix) is an oral, thienopyridine class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.|
|M3233||GW791343 hydrochloride||GW791343 hydrochloride is ahydrochloride salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7.|
|M3185||Ticlopidine hydrochloride||Ticlopidine hydrochloride is a selective P2Y12 receptor antagonist.|
|M3069||Ticagrelor||Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist with Ki of 2 nM respectively.|
|M2954||PPADS Tetrasodium Salt||PPADS tetrasodium salt is a non-selective P2 purinergic antagonist blocking recombinant P2X1, P2X2, P2X3, P2X5 with IC50 of 1-2.6 μM, native P2Y2-like with IC50 of ~ 0.9 mM, and recombinant P2Y4 receptors with IC50 of ~ 15 mM|
|M2869||MRS 2578||MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors.|
|M2234||Prasugrel||Prasugrel is a platelet inhibitor irreversibly binding to P2Y12 receptors.|
|M1909||GW 791343 hydrochloride||GW 791343 hydrochloride is a non-competitive inhibitor of human P2X(7) receptor.|
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