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  Catalog
Abmole Inhibitor Catalog 2017

NLR NOD-like Receptor

Inhibitors

Cat.No.  Name Information
M10136 GSK717 GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor.
M9516 INF39 INF39 is a nontoxic, irreversible NLRP3 inhibitor able to decrease interleukin-1β release from macrophages.
M9376 Dapansutrile (OLT1177) Dapansutrile (OLT1177) is a first-in-class potent, selective and orally active inhibitor of NLRP3 inflammasome.
M9263 CY-09 CY-09 is a selective and direct NLRP3 inhibitor.
M8083 MCC950 sodium salt (CP-456773) MCC950 (CP-456773) sodium salt was found to act as a cytokine release inhibitory drug and inhibitor of the NLRP3 inflammasome.
M7547 NOD-IN-1 NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.74 μM and 6.45 μM, respectively.
M6164 MCC950 MCC950 is a potent, selective NLRP3 inhibitor with IC50 of 7.5 nM and 8.1 nM in BMDMs and HMDMs, respectively.
M5301 Cardamonin Cardamonin is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM, Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway.
M4578 Oridonin Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity.


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