Inhibitors
Cat.No. | Name | Information |
---|---|---|
M9516 | INF39 | INF39 is a nontoxic, irreversible NLRP3 inhibitor able to decrease interleukin-1β release from macrophages. |
M9376 | Dapansutrile | Dapansutrile is a potent, selective and orally active inhibitor of NLRP3 inflammasome. |
M9263 | CY-09 | CY-09 is a selective and direct NLRP3 inhibitor. |
M8083 | CP-456773 sodium salt | CP-456773 sodium salt (MCC950) was found to act as a cytokine release inhibitory drug and inhibitor of the NLRP3 inflammasome. |
M7547 | NOD-IN-1 | NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.74 μM and 6.45 μM, respectively. |
M6164 | MCC950 | MCC950 is a potent, selective NLRP3 inhibitor with IC50 of 7.5 nM and 8.1 nM in BMDMs and HMDMs, respectively. |
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