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MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1

Cat.No.  Name Information
M43924 MLT-943 MLT-943 is a potent, selective, and orally active inhibitor of mucosa-associated lymphoid tissue protein 1 (MALT1) that inhibits IL-2 secretion in PBMC or whole blood with IC50 values of 0.07-0.09 μM and 0.6-0.8 μM, respectively.In addition, MLT-943 possesses anti-inflammatory activity and can be used in studies of FcgR-mediated inflammation .
M20826 JNJ-67856633 Safimaltib (JNJ-67856633) is an orally active, first-in-class, potent, selective mucosa-associated lymphoid tissue protein 1 (MALT1) allosteric inhibitor for studies related to chronic lymphocytic leukemia (CLL).
M3639 MALT1 inhibitor (MI-2) MALT1 inhibitor is an irreversible MALT1 inhibitor with IC50 of 5.84 μM.
M52575 Val-Arg-Pro-DL-Arg-Fluoromethylketone Val-Arg-Pro-DL-Arg-Fluoromethylketone is a potent MALT1 inhibitor.
M45232 Mepazine Mepazine is a potent and selective inhibitor of MALT1 protease, with IC50s of 0.83 and 0.42 μM for inhibition of full-length GSTMALT1 and GSTMALT1 325-760 segments, respectively, and also affects the viability of ABC-DLBCL cells by enhancing apoptosis. Mepazine also affects the viability of ABC-DLBCL cells by enhancing apoptosis.
M43928 MPT-0118 MPT-0118 is an S-enantiomer of methylpiperazine and a MALT1 inhibitor that can be used in studies related to B-cell tumors.
M43927 SGR-1505 SGR-1505 is a MALT1 inhibitor that can be used in studies related to B-cell tumors.
M43926 ABBV-525 ABBV-525 is a MALT1 inhibitor for studies related to B-cell chronic lymphocytic leukemia, diffuse large B-cell lymphoma.
M43925 ONO-7018 ONO-7018 is a MALT1 inhibitor for studies related to non-Hodgkin's lymphoma, chronic lymphocytic leukemia.
M29223 MLT-747  MLT-747 is a potent, selective, allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 14 nM.
M22509 Z-VRPR-FMK Z-VRPR-FMK is an irreversible MALT1 protein inhibitor. Z-VRPR-FMK inhibits the growth and invasion of diffuse large B-cell lymphoma by inhibiting MALT1-induced NF-κB activation and MMP expression.
M21291 MLT-985 MLT-985 is a highly selective inhibitor of MALT1 conformation with an IC50 value of 3 nM.
M14462 MLT-748 MLT-748 is a potent, selective and allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 5 nM.




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