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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M1929 | GW3965 hydrochloride | GW3965 hydrochloride is a selective, orally active non-steroidal synthetic liver X receptor (LXR) agonist. |
| M14461 | BMS-779788 | BMS-779788 is a LXR partial agonist with IC50 values of 68 nM for LXRα and 14 nM for LXRβ. |
| M10627 | RGX-104 hydrochloride | RGX-104 hydrochloride is a small-molecule LXR (liver X receptor) agonist that modulates innate immunity via transcriptional activation of the ApoE gene. |
| M10621 | Iristectorigenin B | Iristectorigenin B is a liver X receptor (LXR) modulator, which stimulates the transcriptional activity of both LXR-α and LXR-β. |
| M10589 | RGX-104 | RGX-104, also known as SB 742881, is a liver X receptor beta (LXR) agonist with potential immunomodulating and antineoplastic activities. |
| M10138 | Yamogenin | Yamogenin (Diosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. |
| M9354 | SR9238 | SR9238 is a liver X receptor (LXR) inverse agonist with IC50s of 214 nM and 43 nM for LXRα and LXRβ, respectively. |
| M8590 | TFCA | TFCA is a Liver X receptor α (LXRα) antagonist that reduces lipid accumulation and fatty liver in mice. |
| M6768 | GSK2033 | GSK2033 is a potent LXR antagonist. |
| M6087 | LXR-623 | LXR-623 is a novel liver X-receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR-α and LXR-β, respectively. It is orally bioavailable and readily passes the blood-brain barrier. |
| M4874 | SR9243 | SR9243 is a potent and selective LXR inverse agonist. |
| M2204 | T0901317 | T0901317 is a potent and selective agonist for both LXRα and LXRβ with an EC50 of ~ 50 nM. |
| M1929 | GW3965 hydrochloride | GW3965 hydrochloride is a selective, orally active non-steroidal synthetic liver X receptor (LXR) agonist. |
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