|M5204||JH-II-127||JH-II-127 is a highly selective LRRK2 inhibitor with an IC50 = 6.5 nM.|
|M4949||LRRK2-IN-1||LRRK2-IN-1 is useful in treatment of Parkinson's disease.|
|M4831||GSK2578215A||GSK2578215A is a potent and selective LRRK2 kinase inhibitor with IC50 of 8.9 nM and 10.9 nM for LRRK2 (G2019S) and LRRK2 (WT), respectively.|
|M3929||PF-06447475||PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC0 of 3 nM/11 nM for Wt LRRK2/G2019S LRRK2 respectively.|
|M3795||GNE-9605||GNE-9605 is a highly potent, selective, and brain-penetrant LRRK2 inhibitor with IC50 of 19 nM.|
|M3649||GNE-7915||GNE-7915 is a highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor with IC50 and Ki of 9 nM and 1 nM, respectively.|
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