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  Catalog
Abmole Inhibitor Catalog 2017

LRRK2 Leucine-rich repeat kinase 2

Inhibitors

Cat.No.  Name Information
M5204 JH-II-127 JH-II-127 is a highly selective LRRK2 inhibitor with an IC50 = 6.5 nM.
M4949 LRRK2-IN-1 LRRK2-IN-1 is useful in treatment of Parkinson's disease.
M4831 GSK2578215A GSK2578215A is a potent and selective LRRK2 kinase inhibitor with IC50 of 8.9 nM and 10.9 nM for LRRK2 (G2019S) and LRRK2 (WT), respectively.
M3929 PF-06447475 PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC0 of 3 nM/11 nM for Wt LRRK2/G2019S LRRK2 respectively.
M3795 GNE-9605 GNE-9605 is a highly potent, selective, and brain-penetrant LRRK2 inhibitor with IC50 of 19 nM.
M3649 GNE-7915 GNE-7915 is a highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor with IC50 and Ki of 9 nM and 1 nM, respectively.


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