|M14002||LPA2 antagonist 1||LPA2 antagonist 1 is a LPA2 antagonist with an IC50 of 17 nM.|
|M14001||FTY720 (S)-Phosphate||FTY720 (S)-Phosphate is an agonist of S1P receptor 1 (S1PR1), used in the research of acute inflammatory diseases such as acute lung injury.|
|M14000||Fingolimod||Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant.|
|M13999||BMS-986020 sodium||BMS-986020 sodium is a high-affinity lysophosphatidic acid receptor 1 (LPA1) antagonist.|
|M13998||ASP-4058||ASP-4058 is a next-generation, selective and oral bioactive agonist for Sphingosine 1-Phosphate receptors 1 and 5 (S1P1 and S1P5), ameliorates rodent experimental autoimmune encephalomyelitis with a favorable safety profile.|
|M11160||1-Oleoyl lysophosphatidic acid sodium||1-Oleoyl Lysophosphatidic acid (1-Oleoyl-Sn-glycero-3-phosphate) sodium is an effective bioactive phospholipid, which is an LPA receptor activator. 1-oleoyl Lysophosphatidic acid sodium promotes mitosis by inducing DNA synthesis.|
|M8994||AM095 free acid||AM095 free acid is a potent LPA1 receptor antagonist which inhibited GTPγS binding to CHO cell membranes overexpressing recombinant human or mouse LPA1 with IC50 values of 0.98 and 0.73 μM, respectively.|
|M8993||BMS-986020||BMS-986020 (also known as AM152) is a potent and selective LPA1 antagonist.|
|M8992||AM966||AM966 is a potent, selective and orally active LPA(1) receptor antagonist which inhibits lung fibrosis in the mouse bleomycin model.|
|M7674||AM095 sodium||AM095 is a potent and selective, orally bioavailable antagonist of lysophosphatidic acid receptor1 (LPA1).|
|M2213||Ki16425||Ki16425 is a LPA receptor antagonist with Ki values of 0.34, 6.5 and 0.93 μM for the human LPA1, LPA2 and LPA3 receptors, respectively.|
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