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Abmole Inhibitor Catalog 2017

LPL Receptor Lysophospholipid receptor

Inhibitors

Cat.No.  Name Information
M8994 AM095 free acid AM095 free acid is a potent LPA1 receptor antagonist which inhibited GTPγS binding to CHO cell membranes overexpressing recombinant human or mouse LPA1 with IC50 values of 0.98 and 0.73 μM, respectively.
M8993 BMS-986020 BMS-986020 (also known as AM152) is a potent and selective LPA1 antagonist.
M8992 AM966 AM966 is a potent, selective and orally active LPA(1) receptor antagonist which inhibits lung fibrosis in the mouse bleomycin model.
M7674 AM095 sodium AM095 is a potent and selective, orally bioavailable antagonist of lysophosphatidic acid receptor1 (LPA1).
M2213 Ki16425 Ki16425 is a LPA receptor antagonist with Ki values of 0.34, 6.5 and 0.93 μM for the human LPA1, LPA2 and LPA3 receptors, respectively.


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