Catalog

JNK Jun N-terminal kinase

Inhibitors

Cat.No.	Name	Information
M9388	Tanzisertib	Tanzisertib (CC-930) is a potent JNK1/2/3 inhibitor with IC50s of 61/7/6 nM, respectively.
M9176	DTP3	DTP3 is a selective GADD45β/MKK7 inhibitor, which inhibits cancer-selective NF-κB survival pathway.
M9175	Vacquinol-1	Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death.
M8946	IQ-1S	IQ-1S is a potent and selective JNK inhibitor with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively.
M8921	Bentamapimod	Bentamapimod, also known as AS602801, is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.
M5145	Anisomycin	Anisomycin is a pyrrolidine antibiotic, which inhibits protein synthesis, and also act as a JNK activator.
M4340	Cinobufagin	Cinobufagin is a cardiotoxic bufanolide steroid secreted by the Asiatic toad Bufo gargarizans.
M3713	YS-49	YS 49 has potential as a therapeutic strategy for the pathogenesis of Ang II-related vascular diseases such as hypertension and atherosclerosis, via the induction of HO-1 gene activity.
M2785	JNK Inhibitor IX	JNK inhibitor IX is a selective and potent JNK inhibitor with pIC50 of 6.5 and 6.7 for JNK2 and JNK3, respectively.
M2076	SP600125	SP600125 is a novel and selective inhibitor of c-Jun N-terminal kinase (JNK), inhibited phosphorylation of c-Jun with an IC50 of 5-10 microM.
M2013	JNK-IN-8	JNK-IN-8 is a selective JNK inhibitor that inhibits phosphorylation of c-Jun.