|M9388||Tanzisertib||Tanzisertib (CC-930) is a potent JNK1/2/3 inhibitor with IC50s of 61/7/6 nM, respectively.|
|M9176||DTP3||DTP3 is a selective GADD45β/MKK7 inhibitor, which inhibits cancer-selective NF-κB survival pathway.|
|M9175||Vacquinol-1||Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death.|
|M8946||IQ-1S||IQ-1S is a potent and selective JNK inhibitor with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively.|
|M8921||Bentamapimod||Bentamapimod, also known as AS602801, is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.|
|M5145||Anisomycin||Anisomycin is a pyrrolidine antibiotic, which inhibits protein synthesis, and also act as a JNK activator.|
|M4340||Cinobufagin||Cinobufagin is a cardiotoxic bufanolide steroid secreted by the Asiatic toad Bufo gargarizans.|
|M3713||YS-49||YS 49 has potential as a therapeutic strategy for the pathogenesis of Ang II-related vascular diseases such as hypertension and atherosclerosis, via the induction of HO-1 gene activity.|
|M2785||JNK Inhibitor IX||JNK inhibitor IX is a selective and potent JNK inhibitor with pIC50 of 6.5 and 6.7 for JNK2 and JNK3, respectively.|
|M2076||SP600125||SP600125 is a novel and selective inhibitor of c-Jun N-terminal kinase (JNK), inhibited phosphorylation of c-Jun with an IC50 of 5-10 microM.|
|M2013||JNK-IN-8||JNK-IN-8 is a selective JNK inhibitor that inhibits phosphorylation of c-Jun.|
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