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  Catalog
Abmole Inhibitor Catalog 2017

JNK Jun N-terminal kinase

Inhibitors

Cat.No.  Name Information
M8946 IQ-1S IQ-1S is a potent and selective JNK inhibitor with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively.
M8921 Bentamapimod Bentamapimod, also known as AS602801, is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.
M5145 Anisomycin Anisomycin is a pyrrolidine antibiotic, which inhibits protein synthesis, and also act as a JNK activator.
M4340 Cinobufagin Cinobufagin is a cardiotoxic bufanolide steroid secreted by the Asiatic toad Bufo gargarizans.
M3713 YS-49 YS 49 has potential as a therapeutic strategy for the pathogenesis of Ang II-related vascular diseases such as hypertension and atherosclerosis, via the induction of HO-1 gene activity.
M2785 JNK Inhibitor IX JNK inhibitor IX is a selective and potent JNK inhibitor with pIC50 of 6.5 and 6.7 for JNK2 and JNK3, respectively.
M2076 SP600125 SP600125 is a novel and selective inhibitor of c-Jun N-terminal kinase (JNK), inhibited phosphorylation of c-Jun with an IC50 of 5-10 microM.
M2013 JNK-IN-8 JNK-IN-8 is a selective JNK inhibitor that inhibits phosphorylation of c-Jun.


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