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JNK Jun N-terminal kinase

Cat.No.  Name Information
M2076 SP600125 SP600125 is a novel and selective inhibitor of c-Jun N-terminal kinase (JNK), inhibited phosphorylation of c-Jun with an IC50 of 5-10 microM.
M14161 SU3327 SU3327 is a potent, selective and substrate-competitive JNK inhibitor with an IC50 of 0.7 μM.
M14159 Juglanin Juglanin, a natural occurring flavonoid, is a JNK acticator, with inflammation and anti-tumor activities. Juglanin can induce apoptosis and autophagy on human breast cancer cells.
M14158 JNK-IN-7 JNK-IN-7 is a potent JNK inhibitor with IC50 of 1.5, 2 and 0.7 nM for JNK1, JNK2 and JNK3, respectively.
M14157 D-JNKI-1 D-JNKI-1 (AM-111) is a highly potent and cell-permeable peptide inhibitor of JNK.
M14156 CC-401 hydrochloride CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM.
M11008 IQ-3 IQ-3 is a specific inhibitor of the c-JNK family and is more selective for JNK3. IQ-3 for JNK1, JNK2, and JNK3 Kd The values are 0.24 μM, 0.29 μM, and 0.066 μM, respectively.
M10695 WHI-P258 WHI-P258 is an inhibitor of JAK3 with a Ki value of 72 μM.
M10633 AS601245 AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50 values of 150, 220, and 70 nM for JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively.
M10365 L-JNKI-1 L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK.
M9718 DB07268 DB07268 is is a potent and selective JNK1 inhibitor, with IC50 of 9 nM.
M9388 Tanzisertib Tanzisertib (CC-930) is a potent JNK1/2/3 inhibitor with IC50s of 61/7/6 nM, respectively.
M9176 DTP3 DTP3 is a selective GADD45β/MKK7 inhibitor, which inhibits cancer-selective NF-κB survival pathway.
M9175 Vacquinol-1 Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death.
M8946 IQ-1S IQ-1S is a potent and selective JNK inhibitor with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively.
M8921 Bentamapimod Bentamapimod, also known as AS602801, is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.
M7395 TCS JNK 6o TCS JNK 6o is a selective JNK inhibitor.
M6503 BI 78D3 BI 78D3 is a selective, competitive JNK inhibitor.
M5145 Anisomycin Anisomycin is a pyrrolidine antibiotic, which inhibits protein synthesis, and also act as a JNK activator.
M4746 Isovitexin Isovitexin, a flavonoid obtained from Asian rice seeds, has antioxidant and anti-inflammatory activities. Isovitexin acts like an inhibitor of JNK1/2 and inhibits NF-κB activation.




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