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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M10395 | MKC-3946 | MKC-3946 is a potent IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines. |
| M9621 | KIRA6 | KIRA6 is a potent type II IRE1α kinase inhibitor with an IC50 of 0.6 µM. |
| M8331 | STF-083010 | STF-083010 is a potent inhibitor of the ER transmembrane protein IRE1, which mediates the unfolded protein response. |
| M5283 | 4μ8C | 4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM. |
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