|M8829||Picropodophyllotoxin||Picropodophyllotoxin is an insulin-like growth factor-I (IGF-I) receptor kinase inhibitor.|
|M3744||NVP-AEW541||NVP-AEW541 is a novel, potent and selective inhibitor of IGF-IR kinase with IC50 value of 0.086.|
|M3397||AG-1024||AG-1024 (Tyrphostin) inhibits IGF-1R autophosphorylation with IC50 of 7 μM, is less potent to IR with IC50 of 57 μM and specifically distinguishes between InsR and IGF-1R (as compared to other tyrphostins).|
|M2411||AXL1717||AXL1717 (picropodophyllin, Picropodophyllotoxin, PPP) is a non-competitive, potent, and specific inhibitor of IGF-1Rα/β with IC50 of 1 nM.|
|M2192||BMS-754807||BMS-754807 is an ATP-competitive dual-kinase inhibitor of IGF-1R and IR with IC50s of 1.8 nM and 1.7 nM, respectively.|
|M2025||PQ401||PQ401 is an insulin growth factor-1 receptor (IGF-1R) inhibitor.|
|M1957||BMS-536924||BMS-536924 is an ATP-competitive IGF-IR and IR inhibitor with IC50 of 100 nM and 73 nM respectively.|
|M1821||OSI-906||OSI-906 (Linsitinib) is a potent, selective, dual ATP-competitive tyrosine kinase inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR) with IC50 values of 35 nM and 75 nM respectively.|
|M1792||XL228||XL228 is a potent multikinase small-molecule inhibitor of insulin-like growth factor type 1 receptor (IGF1R).|
|M1717||GSK1904529A||GSK1904529A selectively inhibits IGF-IR and IR with IC50s of 27 and 25 nmol/L, respectively.|
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