Catalog

Deubiquitinase Deubiquitinase

Inhibitors

Cat.No.	Name	Information
M9871	GSK2643943A	GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor targeting USP20/Ub-Rho with an IC50 of 160 nM.
M9785	ML364	ML364 is a small molecule inhibitor of the deubiquitinase USP2 (IC50=1.1 μM) with potential anticancer activity.
M9654	GRL0617	GRL0617 is a potent, selective and competitive noncovalent inhibitor of SARS PLPro, with IC50 of 0.6 μM and Ki of 0.49 μM.
M9639	SJB2-043	SJB2-043 is an inhibitor of USP1 which targets ID1 degradation in leukemic cells.
M2807	LDN-57444	LDN-57444 is a reversible, competitive proteasome inhibitor for Uch-L1 with IC50 of 0.88 μM, 28-fold selectivity over isoform Uch-L3.
M2565	PR-619	PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs) with EC50 of 1-20 μM.
M2431	b-AP15	b-AP15 is a deubiquitinases inhibitor for 19S proteasomes activity of Ub-AMC cleavage with IC50 of 2.1 μM. *The compound is unstable in solutions, freshly prepared is recommended
M2196	P22077	P22077 is a selective inhibitor of ubiquitin-specific protease (USP) 7 with EC50 of 8.6 μM.
M2195	P5091	P5091 is a potent and selective inhibitor of ubiquitin-specific protease (USP) 7 with IC50 of 4.2 μM.