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Deubiquitinase Deubiquitinase


Cat.No.  Name Information
M10818 FT827 FT827 is a selective covalent inhibitor of ubiquitin-specific protease 7 (USP7) (Ki=4.2 µM)。 FT827 with USP7 Catalytic Domain (USP7CDresidues 208-560) combined, apparent Kd The value is 7.8 μM.
M10817 FT671 FT671 is a potent, non-covalent, selective USP7 inhibitor,IC50 The value is 52 nM, bound to the USP7 catalytic domain Kd The value is 65 nM.
M10753 VLX1570 VLX1570 is a competitive inhibitor of proteasome deuteronase (DUBs),IC50 约10 μM。
M10752 GNE-6776 GNE-6776 is a potent, selective USP7 inhibitor with oral activity.
M10504 IU1-47 IU1-47 is a potent and specific USP14 inhibitor with an IC50 of 0.6 μM.
M9871 GSK2643943A GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor targeting USP20/Ub-Rho with an IC50 of 160 nM.
M9785 ML364 ML364 is a small molecule inhibitor of the deubiquitinase USP2 (IC50=1.1 μM) with potential anticancer activity.
M9654 GRL0617 GRL0617 is a potent, selective and competitive noncovalent inhibitor of SARS PLPro, with IC50 of 0.6 μM and Ki of 0.49 μM.
M9639 SJB2-043 SJB2-043 is an inhibitor of USP1 which targets ID1 degradation in leukemic cells.
M2807 LDN-57444 LDN-57444 is a reversible, competitive proteasome inhibitor for Uch-L1 with IC50 of 0.88 μM, 28-fold selectivity over isoform Uch-L3.
M2565 PR-619 PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs) with EC50 of 1-20 μM.
M2431 b-AP15 b-AP15 is a deubiquitinases inhibitor for 19S proteasomes activity of Ub-AMC cleavage with IC50 of 2.1 μM. *The compound is unstable in solutions, freshly prepared is recommended
M2196 P22077 P22077 is a selective inhibitor of ubiquitin-specific protease (USP) 7 with EC50 of 8.6 μM.
M2195 P5091 P5091 is a potent and selective inhibitor of ubiquitin-specific protease (USP) 7 with IC50 of 4.2 μM.

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