| Cat.No. | Name | Information |
|---|---|---|
| M1861 | Silmitasertib (CX-4945) | CX-4945 (Silmitasertib) is a potent small molecule protein kinase inhibitor that selectively binds to and inhibits the enzyme casein kinase II (CK2). |
| M20060 | WAY-296818 | WAY-296818 is a casein kinase 1δ (CK1d) inhibitor with a pIC50 of 6.5376 M. It is a casein kinase 1δ (CK1d) inhibitor with a pIC50 of 6.5376 M. |
| M20059 | WAY-296817 | WAY-296817 is an AC1 inhibitor with an IC50 value of 2.22 µM against CK-1δ. |
| M16830 | Orobol | Orobol is a major soy isoflavone that inhibits CK1ε, VEGFR2, MAP4K5, MNK1, MUSK, TOPK, and TNIK (IC50=1.24-4.45 μM), as well as PI3K isoforms (IC50=3.46-5.27 μM for PI3K α/β/γ/K/δ). |
| M8823 | TBBz | TBBz is a selective, cell-permeable, ATP-competitive inhibitor of casein kinase 2 (CK2). |
| M8815 | Tyrphostin AG 1112 | Tyrphostin AG 1112 is a potent CK II inhibitor. In addition, Tyrphostin AG 1112 inhibited p210bcr-abl tyrosine kinase with IC50 values of 2 μM, 15 μM, and 20 μM against p210bcr-abl, EGFR, and PDGFR kinases, respectively, in cells. |
| M8125 | Quinalizarin | Quinalizarin is a potent (IC50 = 110 nM), ATP-competitive, and highly selective (IC50 > 1 μM for CK1 and 72 other kinases) inhibitor of casein kinase II (CK2), with a Ki value of approximately 50 nM and an IC50 of 110 nM.Quinalizarin induces apoptosis in some cancer cells. Quinalizarin can induce apoptosis in some cancer cells.) |
| M7123 | PF 5006739 | PF 5006739 is a potent, selective CK1δ/ε inhibitor with IC50s of 3.9 nM and 17.0 nM, respectively, and possesses low nanomolar CK1δ/ε potency in vitro and high kinome selectivity. In addition, PF-5006739 improves glucose tolerance in diet-induced obesity (DIO) and genetic (ob/ob) mouse models. It can be used in studies of psychiatric disorders. |
| M7122 | PF 4800567 hydrochloride | PF 4800567 hydrochloride is a selective casein kinase 1ε inhibitor. |
| M6434 | AMG 548 | AMG 548 is an orally potent and selective inhibitor of p38α (Ki=0.5 nM), slightly selective for p38β (Ki=36 nM) and >1000-fold selective for p38γ and p38δ. In addition, AMG 548 also potently inhibited whole blood LPS-stimulated TNFα (IC50=3 nM) and inhibited Wnt signaling through direct inhibition of Casein kinase 1 isoforms δ and ε. |
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