Inhibitor
| Cat.No. | Name | Information |
|---|---|---|
| M28630 | Inz-5 | Inz-5 is a fungal-selective mitochondrial cytochrome bc1 inhibitor. Inz-5 impairs fungal virulence and prevents the evolution of agent resistance. |
| M28614 | Harzianic acid | Harzianic acid, a tetramic acid derivative, with activity of antimicrobial, antibiofilm formation and biofilm disaggregation. Harzianic acid interferes with biofilm formation by limiting bacterial iron availability. Harzianic acid is also a selective inhibitor of Acetohydroxyacid synthase (AHAS), the first enzyme in the branched-chain amino acid biosynthetic pathway. Harzianic acid can used for herbicide and fungicide. |
| M28438 | L685818 | L685818 is a specific immunophilin ligand. L685818 was neuroregenerative and non-neuroprotective in primary brain cultures. L685818 protects dopaminergic neurons from toxic inhibition of MPP+ and 6-OHDA, reduces tyrosine hydroxylase (TH) loss, and promotes neuronal process regeneration. L685818 is also an antifungal reagent for Cryptococcus neoformans. |
| M28312 | ME1111 | ME1111 is an antifungal agent that is active against dermatophytes. ME1111 is an inhibitor of the succinate dehydrogenase of Trichophyton species. ME1111 has an excellent ability to penetrate human nails and is used for onychomycosis research. |
| M28135 | Thifluzamide | Thifluzamide, a broad-spectrum succinate dehydrogenase inhibitor (SDHI) fungicide, has been widely used in the controlling of a variety of fungal diseases in rice fields. |
| M27886 | Pradimicin A | Pradimicin A (PRM-A) is a potent antifungal agent, with an MIC of 4 μg/mL against Candida rugosa. Pradimicin A has antiviral activities against CoV, HIV and other enveloped viruses. Pradimicin A shows aggregation property, and can recognize d-Man in the presence of Ca2+ ion. |
| M27873 | Voxvoganan | Voxvoganan (LTX-109), a topical antimicrobial, is highly effective against S. aureus with a MIC range of 2 to 4 μg/mL. Voxvoganan can be used for the research of bacterial skin infections, fungal infections and nasal decolonisation of MRSA. |
| M27801 | Saperconazole | Saperconazole (R66905) is a broad-spectrum antifungal triazole and has potent activity against Aspergillus with an MIC90 of 0.19 mg/L. |
| M21502 | FBA-IN-1 | FBA-IN-1 is a Candida albicans-derived, first-in-class covalent transactivation inhibitor of fructofuranose 1,6-bisphosphate aldolase (CaFBA) that inhibits the growth of azole-resistant strain 103 with a MIC80 of 1 μg/mL. |
| M19451 | Kakuol | Kakuol is a natural compound with antifungal activity. |
| M19441 | SSF-109 | SSF-109 is a broad-spectrum fungicide which has protective activity against plant disease. SSF-109 inhibits the biosynthesis of ergosterol at the 14α-demethylation step in Botrytis cinerea. |
| M19413 | Gartanin | Gartanin is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells. |
| M19383 | Aegeline | Aegeline, a main alkaloid, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast. Aegeline restores growth of yeast cells suppressed by either αsyn or Bax. Antioxidant activity. |
| M19364 | Purpurin | Purpurin is a natural anthraquinone compound from Rubia cordifolia L. Purpurin has antidepressant-like effects. |
| M19308 | Coniferin | Coniferin (Laricin) is a glucoside of coniferyl alcohol. Coniferin inhibits fungal growth and melanization. |
| M19162 | Cauloside A | Cauloside A (Leontoside A) is a saponin isolated from Dipsacus asper roots. Cauloside A has potent antifungal activity. |
| M19151 | α-Terpinene | α-Terpinene (Terpilene) is a monoterpene found in the essential oils of a large variety of foods and aromatic plants. α-Terpinene is active against Trypanosoma evansi and has the potential for trypanosomosis treatment. |
| M18311 | Tetrahydrojatrorrhizine | Tetrahydrojatrorrhizine |
| M18176 | Tetradehydropodophyllotoxin | Tetradehydropodophyllotoxin |
| M18143 | 3',4',5,7-Tetramethoxyflavone | 3',4',5,7-Tetramethoxyflavone |
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