Inhibitor/Activator
| Cat.No. | Name | Information |
|---|---|---|
| M5463 | Bithionol | Bithionol is a potent inhibitor of soluble adenylyl cyclase(sAC) and has antibacterial and anthelmintic properties along with algaecide activity. |
| M2191 | Forskolin | Forskolin is a diterpenoid natural product extracted from the hairy throat sphagnum flower (Coleus forskohlii), and is also a eukaryotic adenylate cyclase (AC) activator, which can increase cAMP levels. In addition, Forskolin can be used as a substitute for Oct4 in the induction and maintenance of pluripotent stem cells in mice and promotes osteoblast differentiation in vitro with potential anti-osteoporotic activity. |
| M30674 | Lysipressin acetate | Lysipressin (Lysine vasopressin) acetate is antidiuretic hormone that have been found in pigs and some marsupial families. Lysipressin acetate induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase. |
| M30203 | Lysipressin | Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs and some marsupial families. Lysipressin induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase. |
| M10055 | 2',5'-Dideoxyadenosine | 2′,5′-Dideoxyadenosine is a cell-permeable adenylyl cyclase inhibitor, IC50 = 2.7 μM in detergent-dispersed rat brain preparations. |
| M8787 | ST034307 | ST034307 is a selective inhibitor of adenylyl cyclase 1 (AC1) with IC50 of 2.3 μM, it has analgesic activity. |
| M7874 | KH7 | KH7 is a specific inhibitor of soluble adenylate cyclase (sAC) with IC50 values of 3-10 μM against recombinant sACt proteins (human and others) in cells. KH7 is also an inhibitor of cAMP. |
| M6093 | SQ22536 | SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 μM. It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets. |
| M54475 | Small Cardioactive Peptide B (SCPB) | Small Cardioactive Peptide B (SCPB), a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0 μM, respectively. |
| M53956 | TIP 39, Tuberoinfundibular Neuropeptide | TIP 39, Tuberoinfundibular Neuropeptide is a neuropeptide and parathyroid hormone 2 receptor (PTH2R) agonist. |
| M53285 | PACAP (6-27) (human, ovine, rat) | PACAP (6-27) (human, ovine, rat) is a PACAP receptor antagonist that blocks the canine adrenal catecholamine response to exogenous vasoactive intestinal peptide (VIP). |
| M13886 | Fipexide | Fipexide, a parachloro-phenossiacetic acid derivative. Fipexide is used for senile dementia research. |
| M7031 | NKH 477 | NKH477 (Colforsin dapropate hydrochloride) directly activates the catalytic unit of adenylate cyclase and increases intracellular cAMP. NKH477 can inhibit acute rejection of orthotopic lung allograft in rats by inhibiting proliferation in vivo. |
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